| Date | Location | Result | |
| Nov 21, 2010 | Hillsdale, Mich. | Grand Valley State 3, Indianapolis 2 (15-25,26-24,25-16,23-25,15-9) | Box score |
| Nov 20, 2010 | Hillsdale, Mich. | Indianapolis 3, Hillsdale College 2 (25-21,17-25,21-25,25-20,15-10) | Box score |
| Nov 19, 2010 | Hillsdale, Mich. | Indianapolis 3, NM 1 (25-16,25-18,24-26,25-22) | Box score |
| Nov 14, 2010 | Romeoville, IL | Lewis 3, Indianapolis 1 (25-18,24-26,25-23,25-22) | Box score |
| Nov 13, 2010 | Romeoville, IL | Indianapolis 3, Southern Indiana 0 (25-19,25-14,25-18) | Box score |
| Nov 12, 2010 | Romeoville, IL | Indianapolis 3, Bellarmine 0 (28-26,25-18,26-24) | Box score |
| Nov 05, 2010 | St. Louis, MO | Indianapolis 3, Maryville University 0 (25-17,25-21,25-18) | Box score |
| Nov 02, 2010 | Indianapolis, IN | Indianapolis 3, Saint Joseph's 0 (25-17,25-20,25-13) | Box score |
| Oct 30, 2010 | Indianapolis, IN | Indianapolis 3, Drury 1 (25-16,15-25,25-19,25-15) | Box score |
| Oct 29, 2010 | Indianapolis, Ind. | Indianapolis 3, Rockhurst 2 (25-15,25-20,22-25,22-25,19-17) | Box score |
| Oct 26, 2010 | Indianapolis, IN | Indianapolis 3, Urbana 0 (25-10,25-11,25-9) | Box score |
| Oct 23, 2010 | Louisville, KY | Bellarmine 3, Indianapolis 2 (20-25,25-23,25-20,19-25,15-11) | Box score |
| Oct 22, 2010 | Highland Heights, KY | Indianapolis 3, Northern Kentucky 2 (23-25,25-13,25-23,19-25,15-13) | Box score |
| Oct 16, 2010 | Aurora, IL | Indianapolis 3, NM 0 (25-15,25-22,25-15) | Box score |
| Oct 15, 2010 | Great Lakes Center | Indianapolis 3, Tiffin 1 (25-12,21-25,25-21,25-23) | Box score |
| Oct 15, 2010 | Aurora, IL | Indianapolis 3, Northwood 2 (25-23,23-25,20-25,25-16,15-10) | Box score |
| Oct 09, 2010 | Indianapolis, IN | Indianapolis 3, Southern Indiana 0 (25-19,25-20,25-22) | Box score |
| Oct 08, 2010 | Indianapolis, IN | Indianapolis 3, Kentucky Wesleyan 0 (25-15,25-13,25-14) | Box score |
| Oct 06, 2010 | Indianapolis, IN | Indianapolis 3, Indiana Wesleyan 0 (25-17,25-23,25-17) | Box score |
| Oct 02, 2010 | Springfield, Ill. | Indianapolis 3, UIS 0 (25-12,25-21,25-21) | Box score |
| Oct 01, 2010 | Quincy, Illinois | Indianapolis 3, Quincy 0 (25-13,25-15,25-15) | Box score |
| Sep 28, 2010 | Upland, IN | Taylor University 3, Indianapolis 0 (26-24,27-25,25-23) | Box score |
| Sep 25, 2010 | Indianapolis, IN | Indianapolis 3, Missouri-St. Louis 1 (17-25,25-17,25-21,27-25) | Box score |
| Sep 24, 2010 | Indianapolis, IN | Indianapolis 3, Missouri S&T 0 (25-14,25-19,25-17) | Box score |
| Sep 22, 2010 | Ashland, OH | Ashland University 3, Indianapolis 1 (26-24,25-22,19-25,25-19) | Box score |
| Sep 18, 2010 | Romeoville, IL | Lewis 3, Indianapolis 1 (23-25,25-20,25-22,29-27) | Box score |
| Sep 17, 2010 | UWP Somers, Wis. | UW-Parkside 3, Indianapolis 1 (18-25,25-15,26-24,29-27) | Box score |
| Sep 11, 2010 | Warrensburg, MO | Central Missouri 3, Indianapolis 1 (25-20,25-14,27-29,25-12) | Box score |
| Sep 11, 2010 | Warrensburg, MO | Indianapolis 3, Pittsburg State 1 (25-18,25-15,23-25,25-18) | Box score |
| Sep 10, 2010 | Warrensburg, MO | Indianapolis 3, Eckerd College 1 (25-22,25-13,21-25,25-22) | Box score |
| Sep 10, 2010 | Central Missouri | Indianapolis 3, AAU-VB 0 (25-15,25-18,25-22) | Box score |
| Sep 07, 2010 | Fort Wayne, IN | Indianapolis 3, Indiana Tech 1 (23-25,25-18,25-17,25-18) | Box score |
| Sep 04, 2010 | Indianapolis, IN | Truman 3, Indianapolis 2 (20-25,25-22,25-23,17-25,15-12) | Box score |
| Sep 04, 2010 | Indianapolis, IN | Indianapolis 3, Tusculum 1 (17-25,25-23,25-16,25-17) | Box score |
| Sep 03, 2010 | Indianapolis, IN | Indianapolis 3, Nova Southeastern 1 (25-12,25-17,23-25,25-14) | Box score |
| Sep 03, 2010 | Indianapolis, IN | Indianapolis 3, Wayne State 0 (25-15,25-12,26-24) | Box score |